ABOUT

About CLIME


The Danish Clinical Metabolomics network was kick-started during the Clinical Metabolomics Conference in October 2018.


It was born from a desire to meet the needs of this blooming field:

  

  • A need for more connection between research and clinical practice.
  • A need for people working in the field to find collaborators and get to know what is already possible and ongoing in Denmark and Skåne.



CLIME Board and Scientific Commitee



Industry Outreach

Markus J. Herrgård

Diversity and Inclusion Outreach

Cristina Legido-Quigley


Communication

Asger Wretlind


Chair

Karolina Sulek

Data Science and Informatics Outreach

Madeleine Ernst



Academic Outreach

Kajetan Trošt

Madeleine Ernst

Madeleine Ernst, PhD, is heading the Metabolomics Research Group at the Section for Clinical Mass Spectrometry, Danish Center for Neonatal Screening, Department of Congenital Disorders at Statens Serum Institut. Her group’s research aims at developing population-size mass spectrometry-based metabolomics approaches for predictive, personalized, and preventive diagnostics in early life using the massive sample resource from the Danish National Biobank.


Before starting her position at Statens Serum Institut, she held a postdoctoral position at The Dorrestein Laboratory at the University of California in San Diego. Here, she participated in diverse research projects within computational metabolomics. Among other things, she investigated how the integration of diverse metabolome mining tools, such as mass spectral molecular networking through GNPS and MS2LDA can enhance chemical structural information retrieved in metabolomics experiments.


Markus J. Herrgård

Markus is CTO at the BioInnovation Institute (BII) – the leading early-stage life science startup builder, funder and incubator in Europe. He is responsible for BII's broad technology strategy, infrastructure platforms and partnerships, scouting of new startup building projects, and digital initiatives. Prior to joining BII, Markus was Professor and Director of Data Science and Automation at the Novo Nordisk Foundation Center for Biosustainability (CFB) at DTU. He has also held positions in biotech companies and academia in the US. Markus has extensive experience in innovation, technology development and data science applied to a broad range of life science subfields. He is passionate about improving human and planetary health using a combination of technology and biology.  Markus holds a PhD in Bioengineering from the University of California, San Diego. 


Asger Wretlind

Asger is a Postdoc at King's College London with an affiliation to Steno Diabetes Center, where he did his PhD. His PhD project looked into individual metabolic response to diabetes treatments and investigate biomarkers that can be used to direct personalized treatment.


Kajetan Trošt

Kajetan Trošt is a staff scientist at the Metabolomics platform of the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR), University of Copenhagen. An analytical chemist by training, he specializes in mass spectrometry-based metabolomics, analyzing a wide range of metabolites in complex biological matrices from humans and mice. Dr. Trošt's work spans both basic and applied science, focusing on understanding pathophysiological changes in various diseases. His research contributes to drug development, treatment strategies, and the identification of biomarkers for improved medical diagnostics.


Karolina Sulek

Karolina did her PhD at the Technical University of Denmark and a post-doc at the University of Auckland. Upon return to Denmark she set up a metabolomics facility at the University of Copenhagen, helping researchers at the Novo Nordisk Foundation (NNF) Center for Basic Metabolic Research to understand T2D and obesity through metabolomics profiling. Her interest of the omics opened the path to proteomics at NNF Center for Protein Research in the group of Clinical Proteomics led by Matthias Mann. She is currently a Researcher and Assistant Professor at the Steno Diabetes Center Copenhagen in the group of Systems Medicine led by Cristina Legido-Quigley. Karolina is part of NNF sponsored MicrobLiver consortia, led by Torben Hansen. Her research is focused on clinical multiomics application, including the TARGET project measuring the effects of childhood obesity on liver and gut health.

Cristina Legido-Quigley

Dr Cristina Legido-Quigley is the Head of Systems Medicine at Steno Diabetes Center Copenhagen and an Associate Professor at King’s College London. 


Her main area of interest is neurometabolism and how the brain copes with disease,  as well as finding clinical tests for healthy aging, Alzheimer's, cognition, diabetes and metabolic diseases. Her discoveries span fatty molecules that are important for cognition, small molecules that in liver alert to tissue damage, together with modulating molecular pathways for improving the treatment of diabetes. She is also researching algorithms for better personalised diagnoses in the clinic.


She has been a group leader at King's College London since 2006. In 2018 she moved to Steno a hospital and research center in Denmark to be the Head of Systems Medicine.


Honorary Members


Julie Courraud

MSc, PharmD, PhD

Researcher in metabolomics

Laboratory of Analytical Chemistry

Department of Chemistry, University of Athens

http://trams.chem.uoa.gr/index.html


Co-founder of Clime and previous chair




Douglas McCloskey

PhD

Researcher in metabolomics


Co-founder of Clime and previous board


We also thank the organization committee of our international conferences (CMC2021 and CMC2018).


Finally, we would like to thank the Novo Nordisk Foundation and Michael Bo Jensen for the design of our logo.